C96.6

Unifocal Langerhans-cell histiocytosis

Billable / specificHCC V28 21

C96.6 is a billable, specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes in FY2027.

Inclusion terms

Applicable to

  • Eosinophilic granuloma
  • Histiocytosis X, unifocal
  • Histiocytosis X NOS
  • Langerhans-cell histiocytosis NOS

Includes (from C96)

  • Note: Functional activity
  • Note: All neoplasms are classified in this chapter, whether they are functionally active or not. An additional code from Chapter 4 may be used, to identify functional activity associated with any neoplasm.
  • Note: Morphology [Histology]
  • Note: Chapter 2 classifies neoplasms primarily by site (topography), with broad groupings for behavior, malignant, in situ, benign, etc. The Table of Neoplasms should be used to identify the correct topography code. In a few cases, such as for malignant melanoma and certain neuroendocrine tumors, the morphology (histologic type) is included in the category and codes.
  • Note: Primary malignant neoplasms overlapping site boundaries
  • Note: A primary malignant neoplasm that overlaps two or more contiguous (next to each other) sites should be classified to the subcategory/code .8 ('overlapping lesion'), unless the combination is specifically indexed elsewhere. For multiple neoplasms of the same site that are not contiguous, such as tumors in different quadrants of the same breast, codes for each site should be assigned.
  • Note: Malignant neoplasm of ectopic tissue
  • Note: Malignant neoplasms of ectopic tissue are to be coded to the site mentioned, e.g., ectopic pancreatic malignant neoplasms are coded to pancreas, unspecified (C25.9).

Excludes1

Not coded here — never report together with this code.

  • multifocal and multisysemic (disseminated) Langerhans-cell histiocytosis (C96.0)
  • multifocal and unisystemic Langerhans-cell histiocytosis (C96.5)
  • personal history of other malignant neoplasms of lymphoid, hematopoietic and related tissues (Z85.79) (from C96)

Excludes2

Not included here — may be reported together when both conditions exist.

  • Kaposi's sarcoma of lymph nodes (C46.3) (from C96)
  • secondary and unspecified neoplasm of lymph nodes (C77.-) (from C96)
  • secondary neoplasm of bone marrow (C79.52) (from C96)
  • secondary neoplasm of spleen (C78.89) (from C96)

Also known as

  • Eosinophilic granuloma
  • Histiocytosis X, unifocal
  • Histiocytosis X NOS
  • Langerhans-cell histiocytosis NOS
  • Granuloma, bone, eosinophilic
  • Granuloma, bone, lung
  • Granuloma, eosinophilic
  • Granuloma, eosinophilic, bone
  • Granuloma, eosinophilic, lung
  • Granuloma, lung, eosinophilic
  • Histiocytosis, Langerhans' cell NEC
  • Histiocytosis, Langerhans' cell NEC, unifocal
  • Histiocytosis, mononuclear phagocytes NEC, Langerhans' cells
  • Histiocytosis, X NEC
  • Histiocytosis, X NEC, chronic
  • Histiocytosis, X NEC, unifocal

Parent code

  • C96Other and unspecified malignant neoplasms of lymphoid, hematopoietic and related tissueHeader

Related codes

  • C96.0Multifocal and multisystemic (disseminated) Langerhans-cell histiocytosisBillable
  • C96.2Malignant mast cell neoplasmHeader
  • C96.4Sarcoma of dendritic cells (accessory cells)Billable
  • C96.5Multifocal and unisystemic Langerhans-cell histiocytosisBillable
  • C96.AHistiocytic sarcomaBillable
  • C96.ZOther specified malignant neoplasms of lymphoid, hematopoietic and related tissueBillable
  • C96.9Malignant neoplasm of lymphoid, hematopoietic and related tissue, unspecifiedBillable

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