D53.1

Other megaloblastic anemias, not elsewhere classified

Billable / specific

D53.1 is a billable, specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes in FY2027.

Inclusion terms

Applicable to

  • Megaloblastic anemia NOS

Includes (from D53)

  • megaloblastic anemia unresponsive to vitamin B12 or folate therapy

Excludes1

Not coded here — never report together with this code.

  • Di Guglielmo's disease (C94.0)

Excludes2

Not included here — may be reported together when both conditions exist.

  • autoimmune disease (systemic) NOS (M35.9) (from D53)
  • certain conditions originating in the perinatal period (P00-P96) (from D53)
  • complications of pregnancy, childbirth and the puerperium (O00-O9A) (from D53)
  • congenital malformations, deformations and chromosomal abnormalities (Q00-Q99) (from D53)
  • endocrine, nutritional and metabolic diseases (E00-E88) (from D53)
  • human immunodeficiency virus [HIV] disease (B20) (from D53)
  • injury, poisoning and certain other consequences of external causes (S00-T88) (from D53)
  • neoplasms (C00-D49) (from D53)
  • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94) (from D53)

Also known as

  • Megaloblastic anemia NOS
  • Anemia, achrestic
  • Anemia, deficiency, combined B12 and folate
  • Anemia, dimorphic
  • Anemia, diphasic
  • Anemia, megaloblastic
  • Anemia, megaloblastic, combined B12 and folate deficiency
  • Anemia, megaloblastic, refractory
  • Anemia, megaloblastic, specified type NEC
  • Anemia, megalocytic
  • Anemia, refractory, megaloblastic
  • Megalocytic anemia

Parent code

  • D53Other nutritional anemiasHeader

Related codes

  • D53.0Protein deficiency anemiaBillable
  • D53.2Scorbutic anemiaBillable
  • D53.8Other specified nutritional anemiasBillable
  • D53.9Nutritional anemia, unspecifiedBillable

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