Defects in the complement system
Billable / specificHCC V28 115
D84.1 is a billable, specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes in FY2027.
Inclusion terms
Applicable to
- C1 esterase inhibitor [C1-INH] deficiency
Includes (from D84)
- defects in the complement system
- immunodeficiency disorders, except human immunodeficiency virus [HIV] disease
- sarcoidosis
Excludes1
Not coded here — never report together with this code.
Excludes2
Not included here — may be reported together when both conditions exist.
- autoimmune disease (systemic) NOS (M35.9) (from D84)
- certain conditions originating in the perinatal period (P00-P96) (from D84)
- complications of pregnancy, childbirth and the puerperium (O00-O9A) (from D84)
- congenital malformations, deformations and chromosomal abnormalities (Q00-Q99) (from D84)
- endocrine, nutritional and metabolic diseases (E00-E88) (from D84)
- human immunodeficiency virus [HIV] disease (B20) (from D84)
- injury, poisoning and certain other consequences of external causes (S00-T88) (from D84)
- neoplasms (C00-D49) (from D84)
- symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94) (from D84)
- human immunodeficiency virus [HIV] disease (B20) (from D84)
Also known as
- C1 esterase inhibitor [C1-INH] deficiency
- Angioedema, hereditary
- Angioneurotic edema, hereditary
- Bannister's disease, hereditary
- Defect, defective, complement system
- Deficiency, deficient, C1 esterase inhibitor
- Edema, edematous, angioneurotic, hereditary
- Edema, edematous, circumscribed, acute, hereditary
- Edema, edematous, essential, acute, hereditary
- Edema, edematous, glottis, glottic, glottidis, allergic, hereditary
- Edema, edematous, periodic, hereditary
- Edema, edematous, Quincke's, hereditary
- Giant, urticaria, hereditary
- Quincke's disease or edema, hereditary
- Urticaria, with angioneurotic edema, hereditary
- Urticaria, giant, hereditary
Parent code
- D84Other immunodeficienciesHeader