D89.832

Cytokine release syndrome, grade 2

Billable / specific

D89.832 is a billable, specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes in FY2027.

Inclusion terms

Includes (from D89)

  • defects in the complement system
  • immunodeficiency disorders, except human immunodeficiency virus [HIV] disease
  • sarcoidosis

Excludes1

Not coded here — never report together with this code.

  • autoimmune disease (systemic) NOS (M35.9) (from D89)
  • functional disorders of polymorphonuclear neutrophils (D71-) (from D89)
  • hyperglobulinemia NOS (R77.1) (from D89)
  • monoclonal gammopathy (of undetermined significance) (D47.2) (from D89)

Excludes2

Not included here — may be reported together when both conditions exist.

  • autoimmune disease (systemic) NOS (M35.9) (from D89)
  • certain conditions originating in the perinatal period (P00-P96) (from D89)
  • complications of pregnancy, childbirth and the puerperium (O00-O9A) (from D89)
  • congenital malformations, deformations and chromosomal abnormalities (Q00-Q99) (from D89)
  • endocrine, nutritional and metabolic diseases (E00-E88) (from D89)
  • human immunodeficiency virus [HIV] disease (B20) (from D89)
  • injury, poisoning and certain other consequences of external causes (S00-T88) (from D89)
  • neoplasms (C00-D49) (from D89)
  • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94) (from D89)
  • human immunodeficiency virus [HIV] disease (B20) (from D89)
  • transplant failure and rejection (T86.-) (from D89)

Code first

Sequence the underlying condition first.

  • underlying cause, such as: (from D89.83)
  • complications following infusion, transfusion and therapeutic injection (T80.89-) (from D89.83)
  • complications of transplanted organs and tissue (T86.-) (from D89.83)

Use additional code

Add a code to identify the following, if applicable.

  • code for adverse effect, if applicable, to identify immune checkpoint inhibitors and immunostimulant drugs (T45.AX5) (from D89.83)
  • code to identify associated manifestations (from D89.83)

Also known as

  • Syndrome, cytokine release, grade 2

Parent code

  • D89.83Cytokine release syndromeHeader

Related codes

  • D89.831Cytokine release syndrome, grade 1Billable
  • D89.833Cytokine release syndrome, grade 3Billable
  • D89.834Cytokine release syndrome, grade 4Billable
  • D89.835Cytokine release syndrome, grade 5Billable
  • D89.839Cytokine release syndrome, grade unspecifiedBillable

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