E21.0

Primary hyperparathyroidism

Billable / specific

E21.0 is a billable, specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes in FY2027.

Inclusion terms

Applicable to

  • Hyperplasia of parathyroid
  • Osteitis fibrosa cystica generalisata [von Recklinghausen's disease of bone]

Includes (from E21)

  • Note: All neoplasms, whether functionally active or not, are classified in Chapter 2. Appropriate codes in this chapter (i.e. E05.8, E07.0, E16-E31, E34.-) may be used as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere.

Excludes1

Not coded here — never report together with this code.

  • transitory endocrine and metabolic disorders specific to newborn (P70-P74) (from E21)
  • galactorrhea (N64.3) (from E21)
  • gynecomastia (N62) (from E21)
  • adult osteomalacia (M83.-) (from E21)
  • ectopic hyperparathyroidism (E34.2) (from E21)
  • hungry bone syndrome (E83.81) (from E21)
  • infantile and juvenile osteomalacia (E55.0) (from E21)

Excludes2

Not included here — may be reported together when both conditions exist.

  • familial hypocalciuric hypercalcemia (E83.52) (from E21)

Also known as

  • Hyperplasia of parathyroid
  • Osteitis fibrosa cystica generalisata [von Recklinghausen's disease of bone]
  • Disease, diseased, osteofibrocystic
  • Enlargement, enlarged, parathyroid
  • Hyperparathyroidism, primary
  • Hyperplasia, hyperplastic, parathyroid
  • Hypertrophy, hypertrophic, parathyroid
  • Osteitis, fibrosa NEC, cystica
  • Osteitis, fibrosa NEC, osteoplastica
  • Osteitis, parathyroid
  • Recklinghausen disease, bones
  • Von Recklinghausen, disease, bones

Parent code

  • E21Hyperparathyroidism and other disorders of parathyroid glandHeader

Related codes

  • E21.1Secondary hyperparathyroidism, not elsewhere classifiedBillable
  • E21.2Other hyperparathyroidismBillable
  • E21.3Hyperparathyroidism, unspecifiedBillable
  • E21.4Other specified disorders of parathyroid glandBillable
  • E21.5Disorder of parathyroid gland, unspecifiedBillable

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