Primary insulin-like growth factor-1 (IGF-1) deficiency
Billable / specific
E34.321 is a billable, specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes in FY2027.
Inclusion terms
Applicable to
- Acid-labile subunit gene (IGFALS) defect
- Growth hormone gene 1 (GH1) defect with growth hormone neutralizing antibodies
- Growth hormone insensitivity syndrome (GHIS)
- Insulin-like growth factor 1 gene (IGF1) defect
- Laron type short stature
- Severe primary insulin-like growth factor-1 deficiency (SPIGFD)
- Signal transducer and activator of transcription 5B gene (STAT5b) defect
Includes (from E34)
- Note: All neoplasms, whether functionally active or not, are classified in Chapter 2. Appropriate codes in this chapter (i.e. E05.8, E07.0, E16-E31, E34.-) may be used as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere.
Excludes1
Not coded here — never report together with this code.
- achondroplastic short stature (Q77.4) (from E34.3)
- hypochondroplastic short stature (Q77.4) (from E34.3)
- nutritional short stature (E45) (from E34.3)
- pituitary short stature (E23.0) (from E34.3)
- progeria (E34.8) (from E34.3)
- renal short stature (N25.0) (from E34.3)
- Russell-Silver syndrome (Q87.19) (from E34.3)
- short-limbed stature with immunodeficiency (D82.2) (from E34.3)
- short stature (child) (R62.52) (from E34.3)
- short stature in specific dysmorphic syndromes - code to syndrome - see Alphabetical Index (from E34.3)
- short stature NOS (R62.52) (from E34.3)
- transitory endocrine and metabolic disorders specific to newborn (P70-P74) (from E34)
- galactorrhea (N64.3) (from E34)
- gynecomastia (N62) (from E34)
- pseudohypoparathyroidism (E20.1) (from E34)
Also known as
- Acid-labile subunit gene (IGFALS) defect
- Growth hormone gene 1 (GH1) defect with growth hormone neutralizing antibodies
- Growth hormone insensitivity syndrome (GHIS)
- Insulin-like growth factor 1 gene (IGF1) defect
- Laron type short stature
- Severe primary insulin-like growth factor-1 deficiency (SPIGFD)
- Signal transducer and activator of transcription 5B gene (STAT5b) defect
- Dwarfism, Laron-type
- Short, shortening, shortness, statureNEC, Laron-type
Parent code
- E34.32Genetic causes of short statureHeader