E72.81

Disorders of gamma aminobutyric acid metabolism

Billable / specific

E72.81 is a billable, specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes in FY2027.

Inclusion terms

Applicable to

  • 4-hydroxybutyric aciduria
  • Disorders of GABA metabolism
  • GABA metabolic defect
  • GABA transaminase deficiency
  • GABA-T deficiency
  • Gamma-hydroxybutyric aciduria
  • SSADHD
  • Succinic semialdehyde dehydrogenase deficiency

Includes (from E72)

  • Note: All neoplasms, whether functionally active or not, are classified in Chapter 2. Appropriate codes in this chapter (i.e. E05.8, E07.0, E16-E31, E34.-) may be used as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere.

Excludes1

Not coded here — never report together with this code.

  • transitory endocrine and metabolic disorders specific to newborn (P70-P74) (from E72)
  • androgen insensitivity syndrome (E34.5-) (from E72)
  • congenital adrenal hyperplasia (E25.0) (from E72)
  • hemolytic anemias attributable to enzyme disorders (D55.-) (from E72)
  • Marfan syndrome (Q87.4-) (from E72)
  • 5-alpha-reductase deficiency (E29.1) (from E72)
  • disorders of: (from E72)
  • aromatic amino-acid metabolism (E70.-) (from E72)
  • branched-chain amino-acid metabolism (E71.0-E71.2) (from E72)
  • fatty-acid metabolism (E71.3) (from E72)
  • purine and pyrimidine metabolism (E79.-) (from E72)
  • gout (M1A.-, M10.-) (from E72)

Excludes2

Not included here — may be reported together when both conditions exist.

  • Ehlers-Danlos syndromes (Q79.6-) (from E72)

Also known as

  • 4-hydroxybutyric aciduria
  • Disorders of GABA metabolism
  • GABA metabolic defect
  • GABA transaminase deficiency
  • GABA-T deficiency
  • Gamma-hydroxybutyric aciduria
  • SSADHD
  • Succinic semialdehyde dehydrogenase deficiency
  • Aciduria, 4-hydroxybutyric
  • Aciduria, gamma-hydroxybutyric
  • Defect, defective, GABAmetabolic
  • Deficiency, deficient, GABAtransaminase
  • Deficiency, deficient, GABA-T
  • Deficiency, deficient, succinic semialdehyde dehydrogenase
  • Disorder, gamma aminobutyric acidmetabolism

Parent code

  • E72.8Other specified disorders of amino-acid metabolismHeader

Related codes

  • E72.89Other specified disorders of amino-acid metabolismBillable

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