R65.2

Severe sepsis

Non-billable header

R65.2 is a non-billable header code. Use one of the more specific codes below.

Inclusion terms

Applicable to

  • Infection with associated acute organ dysfunction
  • Sepsis with acute organ dysfunction
  • Sepsis with multiple organ dysfunction
  • Systemic inflammatory response syndrome due to infectious process with acute organ dysfunction

Includes (from R65)

  • Note: This chapter includes symptoms, signs, abnormal results of clinical or other investigative procedures, and ill-defined conditions regarding which no diagnosis classifiable elsewhere is recorded.
  • Note: Signs and symptoms that point rather definitely to a given diagnosis have been assigned to a category in other chapters of the classification. In general, categories in this chapter include the less well-defined conditions and symptoms that, without the necessary study of the case to establish a final diagnosis, point perhaps equally to two or more diseases or to two or more systems of the body. Practically all categories in the chapter could be designated 'not otherwise specified', 'unknown etiology' or 'transient'. The Alphabetical Index should be consulted to determine which symptoms and signs are to be allocated here and which to other chapters. The residual subcategories, numbered .8, are generally provided for other relevant symptoms that cannot be allocated elsewhere in the classification.
  • Note: The conditions and signs or symptoms included in categories R00-R94 consist of:
  • Note: (a) cases for which no more specific diagnosis can be made even after all the facts bearing on the case have been investigated;
  • Note: (b) signs or symptoms existing at the time of initial encounter that proved to be transient and whose causes could not be determined;
  • Note: (c) provisional diagnosis in a patient who failed to return for further investigation or care;
  • Note: (d) cases referred elsewhere for investigation or treatment before the diagnosis was made;
  • Note: (e) cases in which a more precise diagnosis was not available for any other reason;
  • Note: (f) certain symptoms, for which supplementary information is provided, that represent important problems in medical care in their own right.

Excludes2

Not included here — may be reported together when both conditions exist.

  • abnormal findings on antenatal screening of mother (O28.-) (from R65)
  • certain conditions originating in the perinatal period (P04-P96) (from R65)
  • signs and symptoms classified in the body system chapters (from R65)
  • signs and symptoms of breast (N63, N64.5) (from R65)

Code first

Sequence the underlying condition first.

  • underlying infection, such as:
  • infection following a procedure (T81.4-)
  • infections following infusion, transfusion and therapeutic injection (T80.2-)
  • puerperal sepsis (O85)
  • sepsis following complete or unspecified spontaneous abortion (O03.87)
  • sepsis following ectopic and molar pregnancy (O08.82)
  • sepsis following incomplete spontaneous abortion (O03.37)
  • sepsis following (induced) termination of pregnancy (O04.87)
  • sepsis NOS (A41.9)

Use additional code

Add a code to identify the following, if applicable.

  • code to identify specific acute organ dysfunction, such as:
  • acute kidney failure (N17.-)
  • acute respiratory failure (J96.0-)
  • critical illness myopathy (G72.81)
  • critical illness polyneuropathy (G62.81)
  • disseminated intravascular coagulopathy [DIC] (D65)
  • encephalopathy (metabolic) (septic) (G93.41)
  • hepatic failure (K72.0-)

Also known as

  • Infection with associated acute organ dysfunction
  • Sepsis with acute organ dysfunction
  • Sepsis with multiple organ dysfunction
  • Systemic inflammatory response syndrome due to infectious process with acute organ dysfunction

Parent code

  • R65Symptoms and signs specifically associated with systemic inflammation and infectionHeader

More specific codes R65.2

  • R65.20Severe sepsis without septic shockBillable
  • R65.21Severe sepsis with septic shockBillable

Related codes

  • R65.1Systemic inflammatory response syndrome (SIRS) of non-infectious originHeader

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