Z16.22

Resistance to vancomycin related antibiotics

Billable / specific

Z16.22 is a billable, specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes in FY2027.

Inclusion terms

Includes (from Z16)

  • Note: Z codes represent reasons for encounters. A corresponding procedure code must accompany a Z code if a procedure is performed. Categories Z00-Z99 are provided for occasions when circumstances other than a disease, injury or external cause classifiable to categories A00-Y89 are recorded as 'diagnoses' or 'problems'. This can arise in two main ways:
  • Note: (a) When a person who may or may not be sick encounters the health services for some specific purpose, such as to receive limited care or service for a current condition, to donate an organ or tissue, to receive prophylactic vaccination (immunization), or to discuss a problem which is in itself not a disease or injury.
  • Note: (b) When some circumstance or problem is present which influences the person's health status but is not in itself a current illness or injury.
  • Note: The codes in this category are provided for use as additional codes to identify the resistance and non-responsiveness of a condition to antimicrobial drugs.

Excludes1

Not coded here — never report together with this code.

  • Methicillin resistant Staphylococcus aureus infection (A49.02) (from Z16)
  • Methicillin resistant Staphylococcus aureus pneumonia (J15.212) (from Z16)
  • Sepsis due to Methicillin resistant Staphylococcus aureus (A41.02) (from Z16)

Code first

Sequence the underlying condition first.

  • the infection (from Z16)

Parent code

  • Z16.2Resistance to other antibioticsHeader

Related codes

  • Z16.20Resistance to unspecified antibioticBillable
  • Z16.21Resistance to vancomycinBillable
  • Z16.23Resistance to quinolones and fluoroquinolonesBillable
  • Z16.24Resistance to multiple antibioticsBillable
  • Z16.29Resistance to other single specified antibioticBillable

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