D56.1

Beta thalassemia

Billable / specificHCC V28 108

D56.1 is a billable, specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes in FY2027.

Inclusion terms

Applicable to

  • Beta thalassemia major
  • Cooley's anemia
  • Homozygous beta thalassemia
  • Severe beta thalassemia
  • Thalassemia intermedia
  • Thalassemia major

Excludes1

Not coded here — never report together with this code.

  • beta thalassemia minor (D56.3)
  • beta thalassemia trait (D56.3)
  • delta-beta thalassemia (D56.2)
  • hemoglobin E-beta thalassemia (D56.5)
  • sickle-cell beta thalassemia (D57.4-)
  • sickle-cell thalassemia (D57.4-) (from D56)

Excludes2

Not included here — may be reported together when both conditions exist.

  • autoimmune disease (systemic) NOS (M35.9) (from D56)
  • certain conditions originating in the perinatal period (P00-P96) (from D56)
  • complications of pregnancy, childbirth and the puerperium (O00-O9A) (from D56)
  • congenital malformations, deformations and chromosomal abnormalities (Q00-Q99) (from D56)
  • endocrine, nutritional and metabolic diseases (E00-E88) (from D56)
  • human immunodeficiency virus [HIV] disease (B20) (from D56)
  • injury, poisoning and certain other consequences of external causes (S00-T88) (from D56)
  • neoplasms (C00-D49) (from D56)
  • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94) (from D56)

Also known as

  • Beta thalassemia major
  • Cooley's anemia
  • Homozygous beta thalassemia
  • Severe beta thalassemia
  • Thalassemia intermedia
  • Thalassemia major
  • Anemia, Cooley's
  • Anemia, erythroblastic, familial
  • Anemia, erythroblastic, of childhood
  • Anemia, familial erythroblastic
  • Thalassemia, beta
  • Thalassemia, beta, homozygous
  • Thalassemia, beta, major
  • Thalassemia, intermedia
  • Thalassemia, major

Parent code

  • D56ThalassemiaHeader

Related codes

  • D56.0Alpha thalassemiaBillable
  • D56.2Delta-beta thalassemiaBillable
  • D56.3Thalassemia minorBillable
  • D56.4Hereditary persistence of fetal hemoglobin [HPFH]Billable
  • D56.5Hemoglobin E-beta thalassemiaBillable
  • D56.8Other thalassemiasBillable
  • D56.9Thalassemia, unspecifiedBillable

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