D56.4

Hereditary persistence of fetal hemoglobin [HPFH]

Billable / specific

D56.4 is a billable, specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes in FY2027.

Excludes1

Not coded here — never report together with this code.

  • sickle-cell thalassemia (D57.4-) (from D56)

Excludes2

Not included here — may be reported together when both conditions exist.

  • autoimmune disease (systemic) NOS (M35.9) (from D56)
  • certain conditions originating in the perinatal period (P00-P96) (from D56)
  • complications of pregnancy, childbirth and the puerperium (O00-O9A) (from D56)
  • congenital malformations, deformations and chromosomal abnormalities (Q00-Q99) (from D56)
  • endocrine, nutritional and metabolic diseases (E00-E88) (from D56)
  • human immunodeficiency virus [HIV] disease (B20) (from D56)
  • injury, poisoning and certain other consequences of external causes (S00-T88) (from D56)
  • neoplasms (C00-D49) (from D56)
  • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94) (from D56)

Also known as

  • Hemoglobin, fetal, hereditary persistence
  • Persistence, persistent, fetal, hemoglobin, hereditary
  • Persistence, persistent, hemoglobin, fetal

Parent code

  • D56ThalassemiaHeader

Related codes

  • D56.0Alpha thalassemiaBillable
  • D56.1Beta thalassemiaBillable
  • D56.2Delta-beta thalassemiaBillable
  • D56.3Thalassemia minorBillable
  • D56.5Hemoglobin E-beta thalassemiaBillable
  • D56.8Other thalassemiasBillable
  • D56.9Thalassemia, unspecifiedBillable

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