Mast cell activation syndrome and related disorders
Non-billable header
D89.4 is a non-billable header code. Use one of the more specific codes below.
Inclusion terms
Includes (from D89)
- defects in the complement system
- immunodeficiency disorders, except human immunodeficiency virus [HIV] disease
- sarcoidosis
Excludes1
Not coded here — never report together with this code.
- aggressive systemic mastocytosis (C96.21)
- congenital cutaneous mastocytosis (Q82.2)
- (non-congenital) cutaneous mastocytosis (D47.01)
- (indolent) systemic mastocytosis (D47.02)
- malignant mast cell neoplasm (C96.2-)
- malignant mastocytoma (C96.29)
- mast cell leukemia (C94.3-)
- mast cell sarcoma (C96.22)
- mastocytoma NOS (D47.09)
- other mast cell neoplasms of uncertain behavior (D47.09)
- systemic mastocytosis associated with a clonal hematologic non-mast cell lineage disease (SM-AHNMD) (D47.02)
- autoimmune disease (systemic) NOS (M35.9) (from D89)
- functional disorders of polymorphonuclear neutrophils (D71-) (from D89)
- hyperglobulinemia NOS (R77.1) (from D89)
- monoclonal gammopathy (of undetermined significance) (D47.2) (from D89)
Excludes2
Not included here — may be reported together when both conditions exist.
- autoimmune disease (systemic) NOS (M35.9) (from D89)
- certain conditions originating in the perinatal period (P00-P96) (from D89)
- complications of pregnancy, childbirth and the puerperium (O00-O9A) (from D89)
- congenital malformations, deformations and chromosomal abnormalities (Q00-Q99) (from D89)
- endocrine, nutritional and metabolic diseases (E00-E88) (from D89)
- human immunodeficiency virus [HIV] disease (B20) (from D89)
- injury, poisoning and certain other consequences of external causes (S00-T88) (from D89)
- neoplasms (C00-D49) (from D89)
- symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94) (from D89)
- human immunodeficiency virus [HIV] disease (B20) (from D89)
- transplant failure and rejection (T86.-) (from D89)
Parent code
- D89Other disorders involving the immune mechanism, not elsewhere classifiedHeader
More specific codes D89.4
Related codes
- D89.0Polyclonal hypergammaglobulinemiaBillable
- D89.1CryoglobulinemiaBillable
- D89.2Hypergammaglobulinemia, unspecifiedBillable
- D89.3Immune reconstitution syndromeBillable
- D89.8Other specified disorders involving the immune mechanism, not elsewhere classifiedHeader
- D89.9Disorder involving the immune mechanism, unspecifiedBillable