D81.81

Biotin-dependent carboxylase deficiency

Non-billable header

D81.81 is a non-billable header code. Use one of the more specific codes below.

Inclusion terms

Applicable to

  • Multiple carboxylase deficiency

Includes (from D81)

  • defects in the complement system
  • immunodeficiency disorders, except human immunodeficiency virus [HIV] disease
  • sarcoidosis

Excludes1

Not coded here — never report together with this code.

  • biotin-dependent carboxylase deficiency due to dietary deficiency of biotin (E53.8)
  • autoimmune disease (systemic) NOS (M35.9) (from D81)
  • functional disorders of polymorphonuclear neutrophils (D71-) (from D81)
  • autosomal recessive agammaglobulinemia (Swiss type) (D80.0) (from D81)

Excludes2

Not included here — may be reported together when both conditions exist.

  • autoimmune disease (systemic) NOS (M35.9) (from D81)
  • certain conditions originating in the perinatal period (P00-P96) (from D81)
  • complications of pregnancy, childbirth and the puerperium (O00-O9A) (from D81)
  • congenital malformations, deformations and chromosomal abnormalities (Q00-Q99) (from D81)
  • endocrine, nutritional and metabolic diseases (E00-E88) (from D81)
  • human immunodeficiency virus [HIV] disease (B20) (from D81)
  • injury, poisoning and certain other consequences of external causes (S00-T88) (from D81)
  • neoplasms (C00-D49) (from D81)
  • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94) (from D81)
  • human immunodeficiency virus [HIV] disease (B20) (from D81)

Also known as

  • Multiple carboxylase deficiency

Parent code

  • D81.8Other combined immunodeficienciesHeader

More specific codes D81.81

  • D81.810Biotinidase deficiencyBillable
  • D81.818Other biotin-dependent carboxylase deficiencyBillable
  • D81.819Biotin-dependent carboxylase deficiency, unspecifiedBillable

Related codes

  • D81.82Activated Phosphoinositide 3-kinase Delta Syndrome [APDS]Billable
  • D81.89Other combined immunodeficienciesBillable

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