Activated Phosphoinositide 3-kinase Delta Syndrome [APDS]
Billable / specificHCC V28 114
D81.82 is a billable, specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes in FY2027.
Inclusion terms
Applicable to
- p110d-activating mutation causing senescent T cells, lymphadenopathy, and immunodeficiency [PASLI] disease
Includes (from D81)
- defects in the complement system
- immunodeficiency disorders, except human immunodeficiency virus [HIV] disease
- sarcoidosis
Excludes1
Not coded here — never report together with this code.
Excludes2
Not included here — may be reported together when both conditions exist.
- autoimmune disease (systemic) NOS (M35.9) (from D81)
- certain conditions originating in the perinatal period (P00-P96) (from D81)
- complications of pregnancy, childbirth and the puerperium (O00-O9A) (from D81)
- congenital malformations, deformations and chromosomal abnormalities (Q00-Q99) (from D81)
- endocrine, nutritional and metabolic diseases (E00-E88) (from D81)
- human immunodeficiency virus [HIV] disease (B20) (from D81)
- injury, poisoning and certain other consequences of external causes (S00-T88) (from D81)
- neoplasms (C00-D49) (from D81)
- symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94) (from D81)
- human immunodeficiency virus [HIV] disease (B20) (from D81)
Code also
An additional code may be needed.
Also known as
- p110d-activating mutation causing senescent T cells, lymphadenopathy, and immunodeficiency [PASLI] disease
- Disease, diseased, p110d-activating mutation causing senescent T cells, lymphadenopathy, and immunodeficiency [PASLI]
- Syndrome, activated phosphoinositide 3-kinase delta syndrome [APDS]
Parent code
- D81.8Other combined immunodeficienciesHeader